Staff / Senior Scientist, Assay Research

What you will do

Design, plan, and execute experiments to improve the efficiency, accuracy, and scalability of Glyphic’s protein sequencing by expansion (ProSE) process.
Establish novel assay workflows and determine the requirements for novel components needed to support them.
Develop proxy assays that isolate workflow and component variables, accelerating integrated solutions and predicting multi-cycle performance without a full end-to-end run.
Propose, design, and test novel analytical approaches to optimize and build predictive understanding of critical components of the ProSE sequencing process including sample preparation, molecular expansion chemistry, automation, and the integration of these components into a robust end-to-end assay.
Correlate assay findings to the physical characteristics of the system using multimodal characterization, and connect assay outcomes and mechanistic understanding to new component requirements.

Design, plan, and execute experiments to improve the efficiency, accuracy, and scalability of Glyphic’s protein sequencing by expansion (ProSE) process.
Establish novel assay workflows and determine the requirements for novel components needed to support them.
Develop proxy assays that isolate workflow and component variables, accelerating integrated solutions and predicting multi-cycle performance without a full end-to-end run.
Propose, design, and test novel analytical approaches to optimize and build predictive understanding of critical components of the ProSE sequencing process including sample preparation, molecular expansion chemistry, automation, and the integration of these components into a robust end-to-end assay.
Correlate assay findings to the physical characteristics of the system using multimodal characterization, and connect assay outcomes and mechanistic understanding to new component requirements.