DMPK Scientist
Schrödinger, New York +4
About the job
We’re seeking a DMPK Scientist to join us in our mission to transform the discovery of therapeutics!
Our drug discovery and preclinical development team includes a cross-functional group of scientists and drug developers with experience working on all common target classes and therapeutic areas. The group is supported by more than 100 software developers and engineers, as well as a large-scale compute infrastructure to apply our proprietary physics based drug design and optimization platform. Ten of the programs we’ve worked on have progressed into preclinical development, with nine currently in clinical trials and one approved by the FDA.
Who will love this job
- A DMPK analysis expert, who understands ADME principles and applications throughout drug development applications throughout drug discovery and development
- A scientist with a robust background in DMPK who has specialized in the use and application of any of the following:
o In vitro/in vivo drug metabolism or transporter approaches to identify potential ADME liabilities and aid in compound optimization
o PK/PD and PBPK modeling approaches to optimize compound selection, dose optimization, and study design (this includes experience with commonly-used PK/PD software, such as Phoenix/WinNonlin, SimCYP, Monolix, MATLAB SimBiology, or other equivalent software)