Senior Fullstack Engineer
Orchestra Bio, San Francisco
- Pay
- Not listed by the employer
- Work type
- Hybrid
- Level
- Senior
- Area
- Software engineering
- Posted
- Oct 9, 2025
About the role
ABOUT ORCHESTRA
Orchestra helps companies navigate the journey from discovery to medicine by connecting science, operations, and finance in an intelligent platform. We're on a mission to make every R&D dollar count.
Developing new medicines is a societal imperative to improve human health and reduce medical costs. Brilliant science needs effective management to develop breakthrough medicines that reach patients. We aim to bring the same level of sophistication to scientific development that modern tools brought to software development. While software teams can ship updates daily, R&D organizations face unique challenges: years long development cycles, complex interdependencies, and high-stakes decisions that can make or break billion dollar programs.
Founded by early Benchling leaders, we just emerged from stealth with $20M in funding from 8VC, Andreessen Horowitz, Insight Partners, Definition, and Haystack to transform how biotech companies operate. Our customers are working on society's most important challenges, including neurodegeneration, cancer, metabolic disease, and biomanufacturing. We're looking for engineers who are excited about building software that helps scientific organizations operate more effectively.
THE ROLE
We're seeking a Senior Fullstack Engineer to join our growing team in San Francisco. You'll work with our team to create complex but intuitive products to manage R&D.
CHALLENGES YOU'LL TACKLE
Complex Decision Making: Build interactive tools that help organizations model different paths to market for their discoveries, assessing complex trade offs between time, money, and technical risk. Our users need to understand how decisions today affect their programs years into the future.
Organizational Alignment: Create intuitive interfaces that help diverse teams (scientists, program managers, executives) understand how their work connects to broader company goals. This includes designing clear ways to visualize complex dependencies and communicate progress across teams.
Scientific Operations: Design interfaces that scientists and researchers use daily to manage their studies, track progress, and coordinate with their teams. This requires crafting experiences that empower rather than get in the way of work.
AI Powered R&D Management: Leverage LLMs to help teams generate and evaluate scenarios, infer scientific progress and risks from unstructured data, and surface critical insights from across their R&D portfolio.
WHAT SETS YOU APART
Complexity: You understand how to build software for complex, interconnected domains where changes in one area cascade across multiple dimensions. You're excited about creating systems that handle the unique challenges of long term, high stakes R&D programs.
Agency: You're drawn to environments where you can shape both the technical architecture and product direction. You enjoy the responsibility of building foundational systems that will scale, balancing the speed needed at an early stage company with the craftsmanship required for complex, mission critical software.
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Listed on Orchestra Bio's Ashby job board; checked 27 h ago. First seen by us 28 h ago. Being listed doesn't mean the team is actively interviewing. We found this board in a public directory and haven't yet confirmed it against the company's own careers page.