Senior Research Associate
Proxima, Boston
About the job
Team: NeoLink Platform
Location: Boston, MA
Employment Type: Contract
About Proxima
Proxima (formerly VantAI) is advancing an AI-native approach to drug discovery by making protein interactions programmable. Our platform brings together foundation-model machine learning, a scalable data generation engine, and a partnership track record exceeding $5B in collaborations across the world's leading biopharma and tech organizations. We've recently closed an oversubscribed seed round partnering us with an elite group of sophisticated and dedicated VCs including DCVC, Nvidia's Nventures, AIX, Yosemite among others.
Neo-1 is our all-atom foundation model that combines state-of-the-art structure prediction and molecular generation in a single system. Neo-1 enables rapid exploration of chemical and structural space for high value, previously intractable targets, and in particular unlocks small molecule proximity therapeutics like molecular glues with AI for the first time.
In parallel, Proxima is developing an advanced structural interactomics platform built on proprietary cross-linking mass spectrometry (XLMS) technology and a lab equipped with next-generation mass spectrometry instrumentation. This platform produces proteome-scale interactome maps and helps identify small molecules that modulate protein interactions. Together with Neo-1, it creates an integrated system capable of co-folding protein complexes while also generating candidate small molecules to influence those interactions.