Senior / Principal Scientist, Antibody Engineering & Rational Design
Calico , South San Francisco, CA
The role
We are seeking an innovative Senior Scientist / Principal Scientist to bridge the gap between traditional antibody discovery and cutting-edge computational design. In this role, you will serve as the primary scientific liaison between the wet-lab antibody team and our machine learning team, driving the evolution of our "Design-Build-Test-Learn" cycle.
You will be responsible for using internal and external computational tools to generate designs for a variety of discovery campaigns and optimization of antibodies. You will also ensure that the computational predictions are rigorously validated and that the resulting biological data is structured to retrain and refine our internal models. We are looking for a deep expert in therapeutic antibody development who is eager to move beyond traditional random screening and champion a rational, data-driven approach to biologic drug discovery.
What you need
- Ph.D. in molecular biology, biochemistry, biophysics, computational chemistry, structural biology, or related discipline